PBK attenuates paclitaxel‐induced autophagic cell death by suppressing p53 in H460 non‐small‐cell lung cancer cells

PDZ‐binding kinase (PBK) has previously been shown to mediate chemoresistance of cancer cells to anticancer drugs. However, it remains unclear how PBK regulates paclitaxel‐induced cancer cell death. Here, we demonstrate that PBK hinders paclitaxel‐mediated autophagic cell death in H460 non‐small‐cel...

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Detalles Bibliográficos
Autores principales: Park, Jung‐Hwan, Park, Sang‐Ah, Lee, Young‐Ju, Park, Hwan‐Woo, Oh, Sang‐Muk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193173/
https://www.ncbi.nlm.nih.gov/pubmed/32237067
http://dx.doi.org/10.1002/2211-5463.12855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193173/
https://www.ncbi.nlm.nih.gov/pubmed/32237067
http://dx.doi.org/10.1002/2211-5463.12855

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