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CNOT7 depletion reverses natural killer cell resistance by modulating the tumor immune microenvironment of hepatocellular carcinoma

A major obstacle to effective cancer immunotherapy is the tumor immune microenvironment. Natural killer (NK) cell resistance has been suggested as a primary cause of poor prognosis in hepatocellular carcinoma (HCC), which seemingly correlates with CNOT7 overexpression. CNOT7, a cytoplasmic mRNA dead...

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Detalles Bibliográficos
Autores principales: Ren, Chongren, Ren, Xiaojing, Cao, Dujuan, Zhao, Haichao, Zhai, Zhensheng, Li, Huiyu, Li, Yanjun, Fu, Xifeng, He, Jiefeng, Zhao, Haoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193174/
https://www.ncbi.nlm.nih.gov/pubmed/32160402
http://dx.doi.org/10.1002/2211-5463.12836