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A Novel Scaffold-Based Hybrid Multicellular Model for Pancreatic Ductal Adenocarcinoma—Toward a Better Mimicry of the in vivo Tumor Microenvironment

With a very low survival rate, pancreatic ductal adenocarcinoma (PDAC) is a deadly disease. This has been primarily attributed to (i) its late diagnosis and (ii) its high resistance to current treatment methods. The latter specifically requires the development of robust, realistic in vitro models of...

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Detalles Bibliográficos
Autores principales: Gupta, Priyanka, Pérez-Mancera, Pedro A., Kocher, Hemant, Nisbet, Andrew, Schettino, Giuseppe, Velliou, Eirini G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193232/
https://www.ncbi.nlm.nih.gov/pubmed/32391339
http://dx.doi.org/10.3389/fbioe.2020.00290