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In Vivo Development of Polymyxin B Resistance in Klebsiella pneumoniae owing to a 42 bp Deletion in the Sequence of phoQ

Polymyxins resistance has emerged worldwide and is threatening the treatment efficacy of multidrug resistant Klebsiella pneumoniae in humans and animals. In this research, we employed whole-genome sequencing (WGS) to investigate the polymyxin B resistance mechanism in selected polymyxin B-susceptibl...

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Detalles Bibliográficos
Autores principales: Xu, Qingqing, Xu, Teng, Zhuang, Yuan, Liu, Xiaofen, Li, Ying, Chen, Yijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193288/
https://www.ncbi.nlm.nih.gov/pubmed/32382559
http://dx.doi.org/10.1155/2020/5868479