Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin

This study aimed to clarify that organic anion transporters (OATs) mediate the drug–drug interaction (DDI) between imipenem and cilastatin. After co-administration with imipenem, the plasma concentrations and the plasma concentration-time curve (AUC) of cilastatin were significantly increased, while...

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Detalles Bibliográficos
Autores principales: Zhu, Yanna, Huo, Xiaokui, Wang, Changyuan, Meng, Qiang, Liu, Zhihao, Sun, Huijun, Tan, Aiping, Ma, Xiaodong, Peng, Jinyong, Liu, Kexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193450/
https://www.ncbi.nlm.nih.gov/pubmed/32373203
http://dx.doi.org/10.1016/j.ajps.2018.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193450/
https://www.ncbi.nlm.nih.gov/pubmed/32373203
http://dx.doi.org/10.1016/j.ajps.2018.11.006

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