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Phosphorylation of BECLIN-1 by BCR-ABL suppresses autophagy in chronic myeloid leukemia

Autophagy is a genetically regulated process of adaptation to metabolic stress and was recently shown to be involved in the treatment response of chronic myeloid leukemia (CML). However, in vivo data are limited and the molecular mechanism of autophagy regulators in the process of leukemogenesis is...

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Detalles Bibliográficos
Autores principales: Yu, Chuanjiang, Gorantla, Sivahari P., Müller-Rudorf, Alina, Müller, Tony A., Kreutmair, Stefanie, Albers, Corinna, Jakob, Lena, Lippert, Lena J., Yue, Zhenyu, Engelhardt, Monika, Follo, Marie, Zeiser, Robert, Huber, Tobias B., Duyster, Justus, Illert, Anna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193473/
https://www.ncbi.nlm.nih.gov/pubmed/31399521
http://dx.doi.org/10.3324/haematol.2018.212027