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Phosphorylation of BECLIN-1 by BCR-ABL suppresses autophagy in chronic myeloid leukemia
Autophagy is a genetically regulated process of adaptation to metabolic stress and was recently shown to be involved in the treatment response of chronic myeloid leukemia (CML). However, in vivo data are limited and the molecular mechanism of autophagy regulators in the process of leukemogenesis is...
Autores principales: | Yu, Chuanjiang, Gorantla, Sivahari P., Müller-Rudorf, Alina, Müller, Tony A., Kreutmair, Stefanie, Albers, Corinna, Jakob, Lena, Lippert, Lena J., Yue, Zhenyu, Engelhardt, Monika, Follo, Marie, Zeiser, Robert, Huber, Tobias B., Duyster, Justus, Illert, Anna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193473/ https://www.ncbi.nlm.nih.gov/pubmed/31399521 http://dx.doi.org/10.3324/haematol.2018.212027 |
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