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Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

Pharmacokinetic-based prophylaxis of replacement factor VIII (FVIII) products has been encouraged in recent years, but the relationship between exposure (factor VIII activity) and response (bleeding frequency) remains unclear. The aim of this study was to characterize the relationship between FVIII...

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Detalles Bibliográficos
Autores principales: Abrantes, João A., Solms, Alexander, Garmann, Dirk, Nielsen, Elisabet I., Jönsson, Siv, Karlsson, Mats O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193498/
https://www.ncbi.nlm.nih.gov/pubmed/31371418
http://dx.doi.org/10.3324/haematol.2019.217133