Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions

The biological processes related to protein homeostasis in Mycobacterium tuberculosis, the etiologic agent of tuberculosis, have recently been established as critical pathways for therapeutic intervention. Proteins of particular interest are ClpC1 and the ClpC1–ClpP1–ClpP2 proteasome complex. The st...

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Detalles Bibliográficos
Autores principales: Wolf, Nina M., Lee, Hyun, Zagal, Daniel, Nam, Joo-Won, Oh, Dong-Chan, Lee, Hanki, Suh, Joo-Won, Pauli, Guido F., Cho, Sanghyun, Abad-Zapatero, Celerino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193532/
https://www.ncbi.nlm.nih.gov/pubmed/32355042
http://dx.doi.org/10.1107/S2059798320004027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193532/
https://www.ncbi.nlm.nih.gov/pubmed/32355042
http://dx.doi.org/10.1107/S2059798320004027

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