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Rab27a plays a dual role in metastatic propensity of pancreatic cancer

Pancreatic cancer is an aggressive malignancy, often diagnosed at metastatic stages. Several studies have implicated systemic factors, such as extracellular vesicle release and myeloid cell expansion, in the establishment of pre-metastatic niches in cancer. The Rab27a GTPase is overexpressed in adva...

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Detalles Bibliográficos
Autores principales: Kren, Nancy, Michaud, Daniel, Bagchi, Sukriti, Greene, Kevin, Pylayeva-Gupta, Yuliya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193593/
https://www.ncbi.nlm.nih.gov/pubmed/32355248
http://dx.doi.org/10.1038/s41598-020-64248-1