The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice

Secreted animal lectins of the galectin family are key players in cancer growth and metastasis. Here we show that galectin-8 (gal-8) induces the expression and secretion of cytokines and chemokines such as SDF-1 and MCP-1 in a number of cell types. This involves gal-8 binding to a uPAR/LRP1/integrin...

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Detalles Bibliográficos
Autores principales: Shatz-Azoulay, Hadas, Vinik, Yaron, Isaac, Roi, Kohler, Ulrike, Lev, Sima, Zick, Yehiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193594/
https://www.ncbi.nlm.nih.gov/pubmed/32355198
http://dx.doi.org/10.1038/s41598-020-64371-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193594/
https://www.ncbi.nlm.nih.gov/pubmed/32355198
http://dx.doi.org/10.1038/s41598-020-64371-z

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