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Inhibition of PI3K/AKT molecular pathway mediated by membrane estrogen receptor GPER accounts for cryptotanshinone induced antiproliferative effect on breast cancer SKBR-3 cells

BACKGROUND: Breast cancer is the most frequently diagnosed malignancy among women and the second leading cause of cancer death worldwide. Among which nuclear estrogen receptor (nER) negative breast cancer is always with much poor prognosis. Recently, membrane G protein coupled estrogen receptor (GPE...

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Detalles Bibliográficos
Autores principales: Shi, Danning, Zhao, Piwen, Cui, Lixia, Li, Hongbo, Sun, Liping, Niu, Jianzhao, Chen, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193699/
https://www.ncbi.nlm.nih.gov/pubmed/32357920
http://dx.doi.org/10.1186/s40360-020-00410-9