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Pitolisant for Daytime Sleepiness in Patients with Obstructive Sleep Apnea Who Refuse Continuous Positive Airway Pressure Treatment. A Randomized Trial

Rationale: Excessive daytime sleepiness is a common disabling symptom in obstructive sleep apnea syndrome. Objectives: To evaluate the efficacy and safety of pitolisant, a selective histamine H3 receptor antagonist with wake-promoting effects, for the treatment of daytime sleepiness in patients with...

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Detalles Bibliográficos
Autores principales: Dauvilliers, Yves, Verbraecken, Johan, Partinen, Markku, Hedner, Jan, Saaresranta, Tarja, Georgiev, Ognian, Tiholov, Rumen, Lecomte, Isabelle, Tamisier, Renaud, Lévy, Patrick, Scart-Gres, Catherine, Lecomte, Jeanne-Marie, Schwartz, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193861/
https://www.ncbi.nlm.nih.gov/pubmed/31917607
http://dx.doi.org/10.1164/rccm.201907-1284OC