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Pitolisant for Daytime Sleepiness in Patients with Obstructive Sleep Apnea Who Refuse Continuous Positive Airway Pressure Treatment. A Randomized Trial
Rationale: Excessive daytime sleepiness is a common disabling symptom in obstructive sleep apnea syndrome. Objectives: To evaluate the efficacy and safety of pitolisant, a selective histamine H3 receptor antagonist with wake-promoting effects, for the treatment of daytime sleepiness in patients with...
Autores principales: | Dauvilliers, Yves, Verbraecken, Johan, Partinen, Markku, Hedner, Jan, Saaresranta, Tarja, Georgiev, Ognian, Tiholov, Rumen, Lecomte, Isabelle, Tamisier, Renaud, Lévy, Patrick, Scart-Gres, Catherine, Lecomte, Jeanne-Marie, Schwartz, Jean-Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193861/ https://www.ncbi.nlm.nih.gov/pubmed/31917607 http://dx.doi.org/10.1164/rccm.201907-1284OC |
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