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The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
The frequency of antifungal resistance, particularly to the azole class of ergosterol biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected with resistant isolates are exceptionally low. Beyond modification of the drug target, our understanding of the molecul...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194077/ https://www.ncbi.nlm.nih.gov/pubmed/31969561 http://dx.doi.org/10.1038/s41467-019-14191-1 |