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Modeling Clear Cell Renal Cell Carcinoma and Therapeutic Implications

Renal cell carcinoma (RCC) comprises a diverse group of malignancies arising from the nephron. The most prevalent type, clear cell renal cell carcinoma (ccRCC), is characterized by genetic mutations in factors governing the hypoxia signaling pathway, resulting in metabolic dysregulation, heightened...

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Detalles Bibliográficos
Autores principales: Wolf, Melissa M., Rathmell, W. Kimryn, Beckermann, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194123/
https://www.ncbi.nlm.nih.gov/pubmed/32123314
http://dx.doi.org/10.1038/s41388-020-1234-3