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Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease

AIMS: In December 2019, the Coronavirus disease-2019 (COVID-19) virus has emerged in Wuhan, China. In this research, the first resolved COVID-19 crystal structure (main protease) was targeted in a virtual screening study by of FDA approved drugs dataset. In addition, a knowledge gap in relations of...

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Detalles Bibliográficos
Autores principales: Kandeel, Mahmoud, Al-Nazawi, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194560/
https://www.ncbi.nlm.nih.gov/pubmed/32251634
http://dx.doi.org/10.1016/j.lfs.2020.117627