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Something Else to Stress about: Perinatal Stress Attenuates CD8(+) T Cell Activity in Adults
Early-life stress has adverse health effects, but the underlying mechanisms are unclear. Hong et al. demonstrate that perinatal exposure to glucocorticoids in mice reprograms the neuroendocrine stress pathway. This results in reduced glucocorticoid levels in adults, leading to attenuated anti-tumor...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194811/ https://www.ncbi.nlm.nih.gov/pubmed/32294404 http://dx.doi.org/10.1016/j.immuni.2020.03.014 |