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Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase

Interferon-induced transmembrane protein 3 (IFITM3) is a key interferon effector that broadly prevents infection by diverse viruses. However, the cellular factors that control IFITM3 homeostasis and antiviral activity have not been fully elucidated. Using site-specific photo-crosslinking and quantit...

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Detalles Bibliográficos
Autores principales: Wu, Xiaojun, Spence, Jennifer S., Das, Tandrila, Yuan, Xiaoqiu, Chen, Chengjie, Zhang, Yuqing, Li, Yumeng, Sun, Yanan, Chandran, Kartik, Hang, Howard C., Peng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194980/
https://www.ncbi.nlm.nih.gov/pubmed/32243810
http://dx.doi.org/10.1016/j.chembiol.2020.03.004