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Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer

CRISPR-Cas adaptive immune systems protect bacteria and archaea against their invading genetic parasites, including bacteriophages/viruses and plasmids. In response to this immunity, many phages have anti-CRISPR (Acr) proteins that inhibit CRISPR-Cas targeting. To date, anti-CRISPR genes have primar...

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Detalles Bibliográficos
Autores principales: Mahendra, Caroline, Christie, Kathleen A., Osuna, Beatriz A., Pinilla-Redondo, Rafael, Kleinstiver, Benjamin P., Bondy-Denomy, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194981/
https://www.ncbi.nlm.nih.gov/pubmed/32218510
http://dx.doi.org/10.1038/s41564-020-0692-2