Enhanced therapeutic index of an antimicrobial peptide in mice by increasing safety and activity against multidrug-resistant bacteria

The rising prevalence of antibiotic resistance underscores the urgent need for novel antimicrobial agents. Antimicrobial peptides (AMPs) are potentially effective therapeutics that disrupt bacterial membranes regardless of resistance to traditional antibiotics. We have developed engineered cationic...

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Detalles Bibliográficos
Autores principales: Di, Y. P., Lin, Q., Chen, C., Montelaro, R. C., Doi, Y., Deslouches, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195177/
https://www.ncbi.nlm.nih.gov/pubmed/32426473
http://dx.doi.org/10.1126/sciadv.aay6817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195177/
https://www.ncbi.nlm.nih.gov/pubmed/32426473
http://dx.doi.org/10.1126/sciadv.aay6817

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