Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas

Somatic cell nuclear transfer (SCNT) in mammals is an inefficient process that is frequently associated with abnormal phenotypes, especially in placentas. Recent studies demonstrated that mouse SCNT placentas completely lack histone methylation (H3K27me3)-dependent imprinting, but how it affects pla...

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Detalles Bibliográficos
Autores principales: Inoue, Kimiko, Ogonuki, Narumi, Kamimura, Satoshi, Inoue, Hiroki, Matoba, Shogo, Hirose, Michiko, Honda, Arata, Miura, Kento, Hada, Masashi, Hasegawa, Ayumi, Watanabe, Naomi, Dodo, Yukiko, Mochida, Keiji, Ogura, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195362/
https://www.ncbi.nlm.nih.gov/pubmed/32358519
http://dx.doi.org/10.1038/s41467-020-16044-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195362/
https://www.ncbi.nlm.nih.gov/pubmed/32358519
http://dx.doi.org/10.1038/s41467-020-16044-8

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