Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

The periplasmic chaperone SurA plays a key role in outer membrane protein (OMP) biogenesis. E. coli SurA comprises a core domain and two peptidylprolyl isomerase domains (P1 and P2), but its mechanisms of client binding and chaperone function have remained unclear. Here, we use chemical cross-linkin...

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Detalles Bibliográficos
Autores principales: Calabrese, Antonio N., Schiffrin, Bob, Watson, Matthew, Karamanos, Theodoros K., Walko, Martin, Humes, Julia R., Horne, Jim E., White, Paul, Wilson, Andrew J., Kalli, Antreas C., Tuma, Roman, Ashcroft, Alison E., Brockwell, David J., Radford, Sheena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195389/
https://www.ncbi.nlm.nih.gov/pubmed/32358557
http://dx.doi.org/10.1038/s41467-020-15702-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195389/
https://www.ncbi.nlm.nih.gov/pubmed/32358557
http://dx.doi.org/10.1038/s41467-020-15702-1

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