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Lipid-protein interactions modulate the conformational equilibrium of a potassium channel

Cell membranes actively participate in the regulation of protein structure and function. In this work, we conduct molecular dynamics simulations to investigate how different membrane environments affect protein structure and function in the case of MthK, a potassium channel. We observe different ion...

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Detalles Bibliográficos
Autores principales: Gu, Ruo-Xu, de Groot, Bert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195391/
https://www.ncbi.nlm.nih.gov/pubmed/32358584
http://dx.doi.org/10.1038/s41467-020-15741-8