Dynamics of heavy chain junctional length biases in antibody repertoires

Antibody variable domain sequence diversity is generated by recombination of germline segments. The third complementarity-determining region of the heavy chain (CDR H3) is the region of highest sequence diversity and is formed by the joining of heavy chain V(H), D(H) and J(H) germline segments combi...

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Detalles Bibliográficos
Autores principales: Sankar, Kannan, Hoi, Kam Hon, Hötzel, Isidro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195405/
https://www.ncbi.nlm.nih.gov/pubmed/32358517
http://dx.doi.org/10.1038/s42003-020-0931-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195405/
https://www.ncbi.nlm.nih.gov/pubmed/32358517
http://dx.doi.org/10.1038/s42003-020-0931-3

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