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Dynamics of heavy chain junctional length biases in antibody repertoires
Antibody variable domain sequence diversity is generated by recombination of germline segments. The third complementarity-determining region of the heavy chain (CDR H3) is the region of highest sequence diversity and is formed by the joining of heavy chain V(H), D(H) and J(H) germline segments combi...
Autores principales: | Sankar, Kannan, Hoi, Kam Hon, Hötzel, Isidro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195405/ https://www.ncbi.nlm.nih.gov/pubmed/32358517 http://dx.doi.org/10.1038/s42003-020-0931-3 |
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