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Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP

RNase P and MRP are highly conserved, multi-protein/RNA complexes with essential roles in processing ribosomal and tRNAs. Three proteins found in both complexes, Pop1, Pop6, and Pop7 are also telomerase-associated. Here, we determine how temperature sensitive POP1 and POP6 alleles affect yeast telom...

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Detalles Bibliográficos
Autores principales: Garcia, P. Daniela, Leach, Robert W., Wadsworth, Gable M., Choudhary, Krishna, Li, Hua, Aviran, Sharon, Kim, Harold D., Zakian, Virginia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195438/
https://www.ncbi.nlm.nih.gov/pubmed/32358529
http://dx.doi.org/10.1038/s41467-020-15875-9