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DNA methylation of chronic lymphocytic leukemia with differential response to chemotherapy

Acquired resistance to chemotherapy is an important clinical problem and can also occur without detectable cytogenetic aberrations or gene mutations. Chronic lymphocytic leukemia (CLL) is molecularly well characterized and has been elemental for establishing central paradigms in oncology. This promp...

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Detalles Bibliográficos
Autores principales: Yosifov, Deyan Yordanov, Bloehdorn, Johannes, Döhner, Hartmut, Lichter, Peter, Stilgenbauer, Stephan, Mertens, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195470/
https://www.ncbi.nlm.nih.gov/pubmed/32358561
http://dx.doi.org/10.1038/s41597-020-0456-0