Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases

The transcription factor EB (TFEB) regulates the expression of target genes bearing the Coordinated Lysosomal Expression and Regulation (CLEAR) motif, thereby modulating autophagy and lysosomal biogenesis. Furthermore, TFEB can bind to the promoter of autophagy-associated genes and induce the format...

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Detalles Bibliográficos
Autores principales: Zhang, Weihuang, Li, Xiaoyu, Wang, Shujun, Chen, Yanse, Liu, Huafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195473/
https://www.ncbi.nlm.nih.gov/pubmed/32377395
http://dx.doi.org/10.1038/s41420-020-0265-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195473/
https://www.ncbi.nlm.nih.gov/pubmed/32377395
http://dx.doi.org/10.1038/s41420-020-0265-4

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