Cargando…
Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors
Angiogenesis is a necessary process for solid tumor growth. Cellular markers for endothelial cell proliferation are potential targets for identifying the vasculature of tumors in homeostasis. Here we customize the behaviors of engineered cells to recognize Apj, a surface marker of the neovascular en...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195494/ https://www.ncbi.nlm.nih.gov/pubmed/32358530 http://dx.doi.org/10.1038/s41467-020-15729-4 |