Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors

Angiogenesis is a necessary process for solid tumor growth. Cellular markers for endothelial cell proliferation are potential targets for identifying the vasculature of tumors in homeostasis. Here we customize the behaviors of engineered cells to recognize Apj, a surface marker of the neovascular en...

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Detalles Bibliográficos
Autores principales: Wang, Zhifu, Wang, Fan, Zhong, Junjie, Zhu, Tongming, Zheng, Yongtao, Zhao, Tong, Xie, Qiang, Ma, Fukai, Li, Ronggang, Tang, Qisheng, Xu, Feng, Tian, Xueying, Zhu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195494/
https://www.ncbi.nlm.nih.gov/pubmed/32358530
http://dx.doi.org/10.1038/s41467-020-15729-4

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