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Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV

BACKGROUND: Visceral leishmaniasis (VL) treatment in HIV patients very often fails and is followed by high relapse and case-fatality rates. Hence, treatment efficacy assessment is imperative but based on invasive organ aspiration for parasite detection. In the search of a less-invasive alternative a...

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Detalles Bibliográficos
Autores principales: Adriaensen, Wim, Cuypers, Bart, Cordero, Carlota F., Mengasha, Bewketu, Blesson, Séverine, Cnops, Lieselotte, Kaye, Paul M., Alves, Fabiana, Diro, Ermias, van Griensven, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195535/
https://www.ncbi.nlm.nih.gov/pubmed/32361248
http://dx.doi.org/10.1016/j.ebiom.2020.102748