Isoniazid and Rifampicin Produce Hepatic Fibrosis through an Oxidative Stress-Dependent Mechanism

METHODS: A combined dose of INH (50 mg) and RMP (100 mg) per kg body weight per day was administered to mice by oral gavage, 6 days a week, for 4 to 24 weeks for the assessment of liver injury, oxidative stress, and development of hepatic fibrosis, including demonstration of changes in key fibrogene...

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Detalles Bibliográficos
Autores principales: Biswas, Ayan, Santra, Suman, Bishnu, Debasree, Dhali, Gopal Krishna, Chowdhury, Abhijit, Santra, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195633/
https://www.ncbi.nlm.nih.gov/pubmed/32373368
http://dx.doi.org/10.1155/2020/6987295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195633/
https://www.ncbi.nlm.nih.gov/pubmed/32373368
http://dx.doi.org/10.1155/2020/6987295

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