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Precise location of linear epitopes on the capsid surface of feline calicivirus recognized by neutralizing and non-neutralizing monoclonal antibodies

We report the generation, characterization and epitope mapping of a panel of 26 monoclonal antibodies (MAbs) against the VP1 capsid protein of feline calicivirus (FCV). Two close but distinct linear epitopes were identified at the capsid outermost surface (P2 subdomain) of VP1, within the E5′HVR ant...

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Detalles Bibliográficos
Autores principales: Cubillos-Zapata, Carolina, Angulo, Iván, Almanza, Horacio, Borrego, Belén, Zamora-Ceballos, María, Castón, José R., Mena, Ignacio, Blanco, Esther, Bárcena, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195702/
https://www.ncbi.nlm.nih.gov/pubmed/32357948
http://dx.doi.org/10.1186/s13567-020-00785-x