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Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models
The heterogeneous tumor microenvironment (TME) is highly complex and not entirely understood. These complex configurations lead to the generation of oxygen-deprived conditions within the tumor niche, which modulate several intrinsic TME elements to promote immunosuppressive outcomes. Decoding these...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195738/ https://www.ncbi.nlm.nih.gov/pubmed/32357910 http://dx.doi.org/10.1186/s13046-020-01583-1 |