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Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models

The heterogeneous tumor microenvironment (TME) is highly complex and not entirely understood. These complex configurations lead to the generation of oxygen-deprived conditions within the tumor niche, which modulate several intrinsic TME elements to promote immunosuppressive outcomes. Decoding these...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Somshuvra, Calar, Kristin, de la Puente, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195738/
https://www.ncbi.nlm.nih.gov/pubmed/32357910
http://dx.doi.org/10.1186/s13046-020-01583-1