Gypenosides regulate farnesoid X receptor-mediated bile acid and lipid metabolism in a mouse model of non-alcoholic steatohepatitis

BACKGROUND: Gypenosides (Gyp) are the main ingredient of the Chinese medicine, Gynostemma pentaphyllum. They are widely used in Asia as a hepatoprotective agent. Here, we elucidated the mechanism of Gyp in non-alcoholic steatohepatitis (NASH) with a focus on farnesoid X receptor (FXR)-mediated bile...

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Detalles Bibliográficos
Autores principales: Li, Hongshan, Xi, Yingfei, Xin, Xin, Tian, Huajie, Hu, Yiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195801/
https://www.ncbi.nlm.nih.gov/pubmed/32377219
http://dx.doi.org/10.1186/s12986-020-00454-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195801/
https://www.ncbi.nlm.nih.gov/pubmed/32377219
http://dx.doi.org/10.1186/s12986-020-00454-y

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