MicroRNA‐based recombinant AAV vector assembly improves efficiency of suicide gene transfer in a murine model of lymphoma

Recent success in clinical trials with recombinant Adeno‐associated virus (AAV)‐based gene therapy has redirected efforts in optimizing AAV assembly and production, to improve its potency. We reasoned that inclusion of a small RNA during vector assembly, which specifically alters the phosphorylation...

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Detalles Bibliográficos
Autores principales: Khan, Nusrat, Cheemadan, Sabna, Saxena, Himanshi, Bammidi, Sridhar, Jayandharan, Giridhara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196056/
https://www.ncbi.nlm.nih.gov/pubmed/32108448
http://dx.doi.org/10.1002/cam4.2935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196056/
https://www.ncbi.nlm.nih.gov/pubmed/32108448
http://dx.doi.org/10.1002/cam4.2935

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