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Melatonin Attenuates Calcium Deposition from Vascular Smooth Muscle Cells by Activating Mitochondrial Fusion and Mitophagy via an AMPK/OPA1 Signaling Pathway

Mitochondrial fusion/mitophagy plays a role in cardiovascular calcification. Melatonin has been shown to protect against cardiovascular disease. This study sought to explore whether melatonin attenuates vascular calcification by regulating mitochondrial fusion/mitophagy via the AMP-activated protein...

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Detalles Bibliográficos
Autores principales: Chen, Wei Ren, Zhou, Yu Jie, Yang, Jia Qi, Liu, Fang, Wu, Xue Ping, Sha, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196154/
https://www.ncbi.nlm.nih.gov/pubmed/32377301
http://dx.doi.org/10.1155/2020/5298483