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Molecular modeling and docking analysis of aspirin with pde7b in the context of neuro-inflammation

The PDE7B gene encodes 3'5'-cyclic nucleotide phosphodiesterase (PDE) and a known target in cognitive impairments. Therefore, it is of interest to design and development of potential inhibitors with PDE7B with improved binding features. We document that the amino acid residues such as H186...

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Detalles Bibliográficos
Autores principales: Balasundaram, Arthi, David, Darling Chellathai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196167/
https://www.ncbi.nlm.nih.gov/pubmed/32405171
http://dx.doi.org/10.6026/97320630016183