Dehydrocostus lactone inhibits NFATc1 via regulation of IKK, JNK, and Nrf2, thereby attenuating osteoclastogenesis

Excessive and hyperactive osteoclast activity causes bone diseases such as osteoporosis and periodontitis. Thus, the regulation of osteoclast differentiation has clinical implications. We recently reported that dehydrocostus lactone (DL) inhibits osteoclast differentiation by regulating a nuclear fa...

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Detalles Bibliográficos
Autores principales: Lee, Hye In, Lee, Gong-Rak, Lee, Jiae, Kim, Narae, Kwon, Minjeong, Kim, Hyun Jin, Kim, Nam Young, Park, Jin Ha, Jeong, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196184/
https://www.ncbi.nlm.nih.gov/pubmed/31964469
http://dx.doi.org/10.5483/BMBRep.2020.53.4.220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196184/
https://www.ncbi.nlm.nih.gov/pubmed/31964469
http://dx.doi.org/10.5483/BMBRep.2020.53.4.220

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