Expression and in vitro function of anti-cancer mAbs in transgenic Arabidopsis thaliana

The anti-colorectal cancer monoclonal antibody CO17-1A (mAb CO), which recognizes the tumor-associated antigen EpCAM, was expressed in transgenic Arabidopsis plants. PCR and western blot analyses showed the insertion and expression of heavy chain (HC)/HC fused to the KDEL ER retention modif (HCK) an...

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Detalles Bibliográficos
Autores principales: Song, Ilchan, Kang, Yang Joo, Kim, Dae Heon, Kim, Mi Kyung, Ko, Kisung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196188/
https://www.ncbi.nlm.nih.gov/pubmed/31234954
http://dx.doi.org/10.5483/BMBRep.2020.53.4.106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196188/
https://www.ncbi.nlm.nih.gov/pubmed/31234954
http://dx.doi.org/10.5483/BMBRep.2020.53.4.106

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