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Expression and in vitro function of anti-cancer mAbs in transgenic Arabidopsis thaliana
The anti-colorectal cancer monoclonal antibody CO17-1A (mAb CO), which recognizes the tumor-associated antigen EpCAM, was expressed in transgenic Arabidopsis plants. PCR and western blot analyses showed the insertion and expression of heavy chain (HC)/HC fused to the KDEL ER retention modif (HCK) an...
Autores principales: | Song, Ilchan, Kang, Yang Joo, Kim, Dae Heon, Kim, Mi Kyung, Ko, Kisung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196188/ https://www.ncbi.nlm.nih.gov/pubmed/31234954 http://dx.doi.org/10.5483/BMBRep.2020.53.4.106 |
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