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The first quarter of the C-terminal domain of Abelson regulates the WAVE regulatory complex and Enabled in axon guidance

BACKGROUND: Abelson tyrosine kinase (Abl) plays a key role in axon guidance in linking guidance receptors to actin dynamics. The long C-terminal domain (CTD) of Drosophila Abl is important for this role, and previous work identified the ‘first quarter’ (1Q) of the CTD as essential. Here, we link the...

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Detalles Bibliográficos
Autores principales: Cheong, Han Sian Joshua, Nona, Mark, Guerra, Samantha Barbara, VanBerkum, Mark Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196227/
https://www.ncbi.nlm.nih.gov/pubmed/32359359
http://dx.doi.org/10.1186/s13064-020-00144-8