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High expression of folate cycle enzyme MTHFD1L correlates with poor prognosis and increased proliferation and migration in colorectal cancer

Aims: To investigate the expression and clinical significance of methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) in colorectal cancer (CRC) and its effect on CRC cells proliferation and migration. Methods: 59 fresh CRC tissue samples and matched normal tissues, 176 archive CRC tissue sample...

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Detalles Bibliográficos
Autores principales: He, Zhongyun, Wang, Xia, Zhang, Huizhong, Liang, Baoxia, Zhang, Jinling, Zhang, Zhenfeng, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196253/
https://www.ncbi.nlm.nih.gov/pubmed/32368304
http://dx.doi.org/10.7150/jca.35014