HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment

Histone deacetylase inhibitors (HDACis) are well-known epigenetic regulators with therapeutic potential in various diseases. Recent studies have shown that HDACis are involved in immune-mediated anti-cancer effects and may modulate the activity of immunotherapy agents. CG-745, a histone deacetylase...

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Detalles Bibliográficos
Autores principales: Kim, Young-Dae, Park, Sang-Min, Ha, Hae Chan, Lee, A Reum, Won, Heeyoung, Cha, Hyunju, Cho, Sangsook, Cho, Joong Myung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196255/
https://www.ncbi.nlm.nih.gov/pubmed/32368288
http://dx.doi.org/10.7150/jca.44622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196255/
https://www.ncbi.nlm.nih.gov/pubmed/32368288
http://dx.doi.org/10.7150/jca.44622

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