Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke

Acute ischemic stroke treatment faces an unresolved obstacle as capillary reperfusion remains insufficient after thrombolysis and thrombectomy causing neuronal damage and poor prognosis. Hypoxia-induced capillary constriction is mediated by actomyosin contraction in precapillary smooth muscle cells...

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Detalles Bibliográficos
Autores principales: Pénzes, Máté, Túrós, Demeter, Máthé, Domokos, Szigeti, Krisztián, Hegedűs, Nikolett, Rauscher, Anna Ágnes, Tóth, Péter, Ivic, Ivan, Padmanabhan, Parasuraman, Pál, Gabriella, Dobolyi, Árpád, Gyimesi, Máté, Málnási-Csizmadia, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196296/
https://www.ncbi.nlm.nih.gov/pubmed/32373216
http://dx.doi.org/10.7150/thno.42077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196296/
https://www.ncbi.nlm.nih.gov/pubmed/32373216
http://dx.doi.org/10.7150/thno.42077

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