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Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions

OBJECTIVE(S): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, current treatments are not entirely effective. Allantoin is one of the principal compounds in many plants an...

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Detalles Bibliográficos
Autores principales: Komeili Movahhed, Tahereh, Moslehi, Azam, Golchoob, Mohammad, Ababzadeh, Shima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196357/
https://www.ncbi.nlm.nih.gov/pubmed/32373294
http://dx.doi.org/10.22038/ijbms.2019.33553.8012