Investigation of intermediate CAG alleles of the HTT in the general population of Rio de Janeiro, Brazil, in comparison with a sample of Huntington disease‐affected families

BACKGROUND: Huntington disease (HD) (MIM: 143100) is a severe autosomal dominant neurodegenerative disease caused by the expansion of CAG trinucleotides (>35) in the HTT. OBJECTIVE: To investigate the frequency of intermediate CAG alleles (IAs) in individuals residing in Rio de Janeiro city with...

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Detalles Bibliográficos
Autores principales: Apolinário, Thays A., da Silva, Iane dos Santos, Agostinho, Luciana de Andrade, Paiva, Carmen L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196456/
https://www.ncbi.nlm.nih.gov/pubmed/32067426
http://dx.doi.org/10.1002/mgg3.1181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196456/
https://www.ncbi.nlm.nih.gov/pubmed/32067426
http://dx.doi.org/10.1002/mgg3.1181

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