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Hyperpolarized (13)C-pyruvate MRI detects real-time metabolic flux in prostate cancer metastases to bone and liver: a clinical feasibility study

BACKGROUND: Hyperpolarized (HP) (13)C-pyruvate MRI is a stable-isotope molecular imaging modality that provides real-time assessment of the rate of metabolism through glycolytic pathways in human prostate cancer. Heretofore this imaging modality has been successfully utilized in prostate cancer only...

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Detalles Bibliográficos
Autores principales: Chen, Hsin-Yu, Aggarwal, Rahul, Bok, Robert A., Ohliger, Michael A., Zhu, Zi, Lee, Philip, Gordon, Jeremy W., van Criekinge, Mark, Carvajal, Lucas, Slater, James B., Larson, Peder E. Z., Small, Eric J., Kurhanewicz, John, Vigneron, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196510/
https://www.ncbi.nlm.nih.gov/pubmed/31685983
http://dx.doi.org/10.1038/s41391-019-0180-z