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Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation

Genome packaging is a fundamental process in a viral life cycle and a prime target of antiviral drugs. Herpesviruses use an ATP-driven packaging motor/terminase complex to translocate and cleave concatemeric dsDNA into procapsids but its molecular architecture and mechanism are unknown. We report at...

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Detalles Bibliográficos
Autores principales: Yang, Yunxiang, Yang, Pan, Wang, Nan, Chen, Zhonghao, Su, Dan, Zhou, Z. Hong, Rao, Zihe, Wang, Xiangxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196598/
https://www.ncbi.nlm.nih.gov/pubmed/32328903
http://dx.doi.org/10.1007/s13238-020-00710-0