Cargando…
Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation
Genome packaging is a fundamental process in a viral life cycle and a prime target of antiviral drugs. Herpesviruses use an ATP-driven packaging motor/terminase complex to translocate and cleave concatemeric dsDNA into procapsids but its molecular architecture and mechanism are unknown. We report at...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196598/ https://www.ncbi.nlm.nih.gov/pubmed/32328903 http://dx.doi.org/10.1007/s13238-020-00710-0 |